Editor's Note Washington University School of Medicine in St Louis is the clinical coordinating center for a new worldwide clinical trial to test whether the vaccine for measles, mumps, and rubella (MMR) can protect frontline healthcare workers (HCWs) against COVID-19. The researchers say there are two main reasons why the…

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Editor's Note In this study from Russia’s Gamaleya National Research Center for Epidemiology and Microbiology, researchers found that a heterologous COVID-19 vaccine based on recombinant human adenovirus type 26 (rAD26) and type 5 (rAD5) had a good safety profile over 42 days and induced strong antibody responses in all participants…

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Editor's Note This prospective meta-analysis from the World Health Organization (WHO) Rapid Evidence Appraisal for COVID-19 Therapies, which pooled data from seven randomized clinical trials of critically ill patients with COVID-19, finds that administration of systemic corticosteroids, compared with usual care or placebo, was associated with lower 28-day all-cause mortality.…

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Editor's Note Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health told the Kaiser Health News on September 1 that a COVID-19 vaccine could be available earlier than expected if clinical trial results are overwhelmingly positive. An independent Data and…

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Editor's Note This study by researchers from Iceland finds that antibodies against COVID-19 remained stable 4 months after diagnosis. The researchers measured antibodies in serum samples from 30,576 people in Iceland, using six assays (including two pan-immunoglobulin (pan-Ig) assays). They then tested 2,102 samples collected from 1,237 people up to…

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Editor's Note This study, led by economists from Washington University in St Louis, finds that the ideal COVID-19 vaccine policy should emphasize age more than work-exposure risk for vaccination priority. To provide a best-practice scenario to supplement a vaccine distribution strategy, the researchers tracked eight age groups in more than…

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Editor's Note In this study from Mount Sinai Hospital and School of Medicine, New York City, researchers identify two markers of inflammation that reliably predict the severity of COVID-19 and likelihood of survival. A total of 1,484 patients were followed up to 41 days after admission, and the findings were…

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Editor's Note The University Hospitals Cleveland Medical Center (UH) announced August 24 that it will participate as a study site for the Phase 2/3 global trial of the Pfizer/BioNTech investigational COVID-19 vaccine. UH is one of approximately 120 clinical investigational sites around the world that will collectively enroll up to…

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Editor's Note This study led by researchers from the Stanford University School of Medicine finds that immunological deviations and lapses determine whether individuals get mild or severe cases of COVID-19. The researchers analyzed the immune response in 76 patients with COVID-19 and in 69 healthy individuals. Most patients with severe…

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Editor's Note The National Institutes of Health (NIH) on August 5 announced the launch of the Medical Imaging and Data Resource Center, which will create new tools using artificial intelligence (AI) and medical imaging to diagnose and personalize therapies for COVID-19 patients. The Center will build a large repository of…

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