Editor's Note: A successful test of a genetically modified pig liver attached to a brain-dead human body could have significant implications for liver failure patients, the Associated Press reported January 18. Conducted at the University of Pennsylvania, the tested method is similar to kidney dialysis in that the genetically modified…

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Editor's Note: A recent study reveals individuals with obesity or metabolic disorder could have a higher risk of experiencing graft function deterioration (GFD), while individuals with metabolically healthy overweight or obesity (MHO) had an elevated risk. Results were published December 27 in JAMA Network Open. The cohort study examined 1260 adult…

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Editor’s Note Penn Medicine celebrated a significant milestone on December 6—its 100th paired kidney exchange surgery in 12 months set a world record for the most kidney paired donation transplants in a year. The announcement was published in an EurekAlert! December 12 press release. Penn Medicine launched its Center for…

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Editor's Note Researchers from Europe used an epigenetic clock to accurately measure biological aging in a clinical setting, Wiley October 12 reports. The study, titled "Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing," was published in the Journal of Internal Medicine. The researchers…

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Editor's Note An 8-year-old girl in the UK has been able to live a normal life without immunosuppressants following a kidney transplant in which both the organ and stem cells came from the same donor, The Independent October 12 reports. The patient was able to stop taking immunosuppressant drugs a…

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Editor's Note A quality improvement study led by clinicians at the Mayo Clinic in Jacksonville, FL, improved clinical alarm management skills and reduced alarm fatigue and desensitization among nurses in a surgical intensive care unit. The study included 115 direct-care nurses working full-time, modified full-time, or part-time schedules in a…

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Editor's Note This study, led by researchers at the Smidt Heart Institute at Cedars-Sinai Medical Center, Los Angeles, finds that from August 2020 through September 2021, 7% of lung transplantations in the US were performed in patients with COVID-19-related respiratory failure. In this analysis of 3,039 lung transplants, 214 were…

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Editor's Note This study led by researchers at the University of Texas Southwestern Medical Center, Dallas, finds that although COVID-19’s effect on access to liver transplantation has been all-pervasive, minorities have been disproportionately affected—especially those with public insurance. During the initial wave of COVID-19, organ transplantation was classified as a…

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Editor's Note The opioid epidemic has expanded the pool of overdose-death donors (ODDs) for heart transplantation. Even though ODDs have higher rates of hepatitis C, cardiac allograft quality indices are favorable, and recipient outcomes are similar to those with non-ODD hearts, this study finds. Of 15,904 heart transplant donors analyzed,…

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Editor's Note In patients without HCV infection who received a heart or lung transplant from HCV-infected donors, treatment with a 4-week antiviral regimen prevented establishment of HCV infection, this study finds. Of 44 patients enrolled in the study, 36 received lung transplants and 8 received heart transplants. All of the…

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