Transplant

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April 2024
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Heart transplant research proves out 24-hour organ preservation method

Editor's Note A new method of organ preservation could allow researchers a much longer window to keep transplanted organs alive. Medical Xpress reported on the findings April 5.   Typically, hearts awaiting transplant are maintained in cold static storage – in which they are kept on ice until transplanted and…

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By: Brita Belli
April 12, 2024
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New hope for Black kidney disease patients awaiting organ transplants

Editor's Note A standard kidney function test has been underestimating the seriousness of disease in Black patients, delaying their eligibility for transplants, The Associated Press reported March 31. Now, that test is changing – and Black patients awaiting kidneys are moving up the list.  Among other factors, transplant eligibility is…

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By: Brita Belli
April 1, 2024
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Donor hearts denied more often to male, black male transplant candidates

Editor's Note New research shows transplant center teams are more to likely reject offers of donor hearts to black men and men than black women and white women, MedPage Today reported on March 25. “The cumulative probability of a donor heart being accepted by the transplant center team was most…

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By: Matt Danford
March 28, 2024
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Surgeons complete first successful animal-to-human kidney transplant

Editor's Note A 62-year-old man in Weymouth, Massachusetts is reportedly recovering well several days after receiving the first kidney to be transplanted into a living person. As noted in a March 21 report in the Boston Globe, the operation at Massachusetts General Hospital marked a new milestone in the effort…

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By: Matt Danford
March 21, 2024
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Machine learning study shows AI’s potential for predicting kidney transplant outcomes

Editor's Note: Artificial intelligence (AI) leveraging machine learning (ML) and natural language processing (NLP, a subset of machine learning) models can help identify donors with kidneys unsuitable for organ transplant, according to a study published November 1 in Jama Surgery. Despite the unmet need, many deceased-donor kidneys are discarded or…

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By: Matt Danford
January 30, 2024
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Pig liver test shows promise for future human transplants

Editor's Note: A successful test of a genetically modified pig liver attached to a brain-dead human body could have significant implications for liver failure patients, the Associated Press reported January 18. Conducted at the University of Pennsylvania, the tested method is similar to kidney dialysis in that the genetically modified…

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By: Matt Danford
January 29, 2024
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Metabolic conditions increase risk of kidney graft function deterioration

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Editor's Note: A recent study reveals individuals with obesity or metabolic disorder could have a higher risk of experiencing graft function deterioration (GFD), while individuals with metabolically healthy overweight or obesity (MHO) had an elevated risk. Results were published December 27 in JAMA Network Open. The cohort study examined 1260 adult…

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By: Matt Danford
January 19, 2024
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Penn Medicine sets world record with 100 kidney paired donation surgeries in 1 year

Editor’s Note Penn Medicine celebrated a significant milestone on December 6—its 100th paired kidney exchange surgery in 12 months set a world record for the most kidney paired donation transplants in a year. The announcement was published in an EurekAlert! December 12 press release. Penn Medicine launched its Center for…

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By: Brita Belli
December 12, 2023
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New epigenetic clock provides clues to accelerated aging in chronic kidney disease

Editor's Note Researchers from Europe used an epigenetic clock to accurately measure biological aging in a clinical setting, Wiley October 12 reports. The study, titled "Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing," was published in the Journal of Internal Medicine. The researchers…

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By: Brita Belli
October 13, 2023
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Stem cells from organ donor increase tolerance following transplant

Editor's Note An 8-year-old girl in the UK has been able to live a normal life without immunosuppressants following a kidney transplant in which both the organ and stem cells came from the same donor, The Independent October 12 reports. The patient was able to stop taking immunosuppressant drugs a…

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By: Brita Belli
October 13, 2023
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