Transplant

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March 2024
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Machine learning study shows AI’s potential for predicting kidney transplant outcomes

Editor's Note: Artificial intelligence (AI) leveraging machine learning (ML) and natural language processing (NLP, a subset of machine learning) models can help identify donors with kidneys unsuitable for organ transplant, according to a study published November 1 in Jama Surgery. Despite the unmet need, many deceased-donor kidneys are discarded or…

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By: Matt Danford
January 30, 2024
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Pig liver test shows promise for future human transplants

Editor's Note: A successful test of a genetically modified pig liver attached to a brain-dead human body could have significant implications for liver failure patients, the Associated Press reported January 18. Conducted at the University of Pennsylvania, the tested method is similar to kidney dialysis in that the genetically modified…

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By: Matt Danford
January 29, 2024
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Metabolic conditions increase risk of kidney graft function deterioration

JAMA (healthcare publication) Network logo

Editor's Note: A recent study reveals individuals with obesity or metabolic disorder could have a higher risk of experiencing graft function deterioration (GFD), while individuals with metabolically healthy overweight or obesity (MHO) had an elevated risk. Results were published December 27 in JAMA Network Open. The cohort study examined 1260 adult…

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By: Matt Danford
January 19, 2024
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Penn Medicine sets world record with 100 kidney paired donation surgeries in 1 year

Editor’s Note Penn Medicine celebrated a significant milestone on December 6—its 100th paired kidney exchange surgery in 12 months set a world record for the most kidney paired donation transplants in a year. The announcement was published in an EurekAlert! December 12 press release. Penn Medicine launched its Center for…

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By: Brita Belli
December 12, 2023
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New epigenetic clock provides clues to accelerated aging in chronic kidney disease

Editor's Note Researchers from Europe used an epigenetic clock to accurately measure biological aging in a clinical setting, Wiley October 12 reports. The study, titled "Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing," was published in the Journal of Internal Medicine. The researchers…

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By: Brita Belli
October 13, 2023
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Stem cells from organ donor increase tolerance following transplant

Editor's Note An 8-year-old girl in the UK has been able to live a normal life without immunosuppressants following a kidney transplant in which both the organ and stem cells came from the same donor, The Independent October 12 reports. The patient was able to stop taking immunosuppressant drugs a…

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By: Brita Belli
October 13, 2023
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CEASE, Philips education, skills training improve alarm monitoring practices in surgical ICU

Editor's Note A quality improvement study led by clinicians at the Mayo Clinic in Jacksonville, FL, improved clinical alarm management skills and reduced alarm fatigue and desensitization among nurses in a surgical intensive care unit. The study included 115 direct-care nurses working full-time, modified full-time, or part-time schedules in a…

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By: Lindsay Botts
April 13, 2023
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Lung transplant for COVID-19-related respiratory failure

Editor's Note This study, led by researchers at the Smidt Heart Institute at Cedars-Sinai Medical Center, Los Angeles, finds that from August 2020 through September 2021, 7% of lung transplantations in the US were performed in patients with COVID-19-related respiratory failure. In this analysis of 3,039 lung transplants, 214 were…

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By: Judy Mathias
January 27, 2022
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Widening of racial, socioeconomic healthcare gap for organ transplant patients during COVID-19

Editor's Note This study led by researchers at the University of Texas Southwestern Medical Center, Dallas, finds that although COVID-19’s effect on access to liver transplantation has been all-pervasive, minorities have been disproportionately affected—especially those with public insurance. During the initial wave of COVID-19, organ transplantation was classified as a…

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By: Judy Mathias
September 16, 2021
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Opioid epidemic increases number of hearts available for transplant

Editor's Note The opioid epidemic has expanded the pool of overdose-death donors (ODDs) for heart transplantation. Even though ODDs have higher rates of hepatitis C, cardiac allograft quality indices are favorable, and recipient outcomes are similar to those with non-ODD hearts, this study finds. Of 15,904 heart transplant donors analyzed,…

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By: Judy Mathias
June 6, 2019
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