Tag: Immunization

FDA recommends updating boosters to target Omicron

Editor's Note The Food and Drug Administration’s (FDA’s) Vaccines and Related Biological Products Advisory Committee on June 28 recommended updating the composition of COVID-19 booster vaccines to target the Omicron variant. The Committee noted that booster doses consisting of an Omicron monovalent or bivalent vaccine could improve neutralizing antibody responses…

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By: Judy Mathias
June 30, 2022
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Newer COVID-19 subvariants show substantial escape from vaccination, previous infection immunity

Editor's Note In a letter published in the New England Journal of Medicine, researchers at Beth Israel Deaconess Medical Center, Boston, report that the three Omicron subvariants (BA.2.12.1, BA.4, and BA.5) currently dominant in the US substantially escape neutralizing antibodies induced by both vaccination and previous COVID-19 infection. The researchers…

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By: Judy Mathias
June 23, 2022
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CDC lifts pre-departure COVID-19 testing for international travelers

Editor's Note The Centers for Disease Control and Prevention (CDC) on June 10 announced that it will no longer require international travelers to have a negative COVID-19 test before flying to the US, effective June 12. The CDC continues to recommend that travelers flying to the US get tested as…

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By: Judy Mathias
June 13, 2022
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Protection, waning of immunity to COVID-19 after infection, vaccination

Editor's Note This Israeli study finds that individuals previously infected with COVID-19, regardless of whether they had been vaccinated, had more protection against reinfection than those who were vaccinated (Pfizer-BioNTech vaccine) but previously uninfected. Among the findings for the number of COVID-19 cases per 100,000 person days since vaccination or…

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By: Judy Mathias
June 8, 2022
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Association of COVID-19 booster and Omicron in the NBA

Editor's Note This study, led by researchers at IQVIA, Durham, North Carolina, finds that in a young, healthy, highly vaccinated cohort of players and staff in the National Basketball Association (NBA), booster vaccinations were associated with a significant reduction in COVID-19 infections during the Omicron wave. Of 2,613 players and…

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By: Judy Mathias
June 7, 2022
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Association of COVID-19 vaccination during pregnancy with COVID-19 risk in infants

Editor's Note This Norwegian study finds that maternal COVID-19 vaccination during the second or third trimester of pregnancy was associated with a reduced risk of COVID-19 within the first 4 months of life of their infants. Of 21,643 infants analyzed, 9,739 (45%) were born to women who received a second…

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By: Judy Mathias
June 2, 2022
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Occurrence, transmission of asymptomatic vs symptomatic COVID-19 infections

Editor's Note Based on this update of a systematic review and meta-analysis of 130 studies, led by researchers from the University of Bern, Switzerland, most COVID-19 infections were not persistently asymptomatic, and asymptomatic infections were less infectious than symptomatic infections. Because of variability among studies, the meta-analysis did not calculate…

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By: Judy Mathias
May 31, 2022
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Transmission of COVID-19 by vaccinated, unvaccinated individuals

Editor's Note This South Korean study finds that fully vaccinated individuals have a shorter duration of viable viral shedding and a lower rate of secondary transmission than partially vaccinated or unvaccinated individuals. This study uses 2 cohorts to separately determine the transmissibility of COVID-19 according to vaccination status (ie, fully…

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By: Judy Mathias
May 26, 2022
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Age patterns of COVID-19 mortality by race, ethnicity, gender

Editor's Note This study led by researchers from the University of Pennsylvania, Philadelphia, finds that from the second (November 2020 to February 2021) through the third periods (July to October 2021) of the COVID-19 pandemic, declines in mortality for various racial, ethnic, and gender combinations were especially large for those…

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By: Judy Mathias
May 24, 2022
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ECRI: Time to move to scheduled COVID-19 vaccinations

Editor's Note In a May 18 position statement, ECRI recommends that it’s time to move to a regularly scheduled COVID-19 vaccine booster model. “Moving to a regular vaccine schedule will increase clarity and confidence about what actions to take and when, compared to the current piecemeal, wait-and-see approach,” says Marcus…

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By: Judy Mathias
May 19, 2022
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