Disparities in US COVID-19 vaccine distribution
Editor's Note This study led by researchers at the University of California, San Diego, finds that healthcare facilities in counties with higher Black composition and rural areas with large Hispanic populations were less likely to serve as COVID-19 vaccine administration locations during the initial rollout in May 2021. At that…
Effect of state COVID-19 vaccine mandates on staff vaccinations
Editor's Note This cohort study of nursing homes in 38 states, led by the University of Rochester Medical Center, Rochester, New York, finds that states with a COVID-19 mandate had an increase in staff vaccinations compared with states with no mandates and no worsening of staffing shortages following the mandates.…
Effectiveness of COVID-19 vaccination in preventing reinfection
Editor's Note This study by researchers from Brown University, Providence, Rhode Island, finds that completing a primary vaccination series after recovering from COVID-19 reduces the risk of reinfection by about half. A total of 95,000 Rhode Island residents participated in this cohort study, including residents and employees of long-term congregate…
Association between vaccination and MI, stroke after COVID-19 infection
Editor's Note This Korean study finds that full COVID-19 vaccination was associated with a reduced risk of acute myocardial infarction (MI) and ischemic stroke after being infected with COVID-19. Of 592,719 patients with COVID-19 during the study period, 231,037 were included in the analysis, of whom 62,727 were never vaccinated…
COVID-19 vaccination perspectives, infections among first responders
Editor's Note This study, led by the University of Miami and sponsored by the CDC, finds that unvaccinated first responders (eg, law enforcement officers, firefighters, and others) were more likely to develop COVID-19 and less likely to believe in the effectiveness and safety of vaccines than their vaccinated counterparts. Of…
Long-term immune response to COVID-19 in children, adults
Editor's Note This Italian study describes the long-term features of the immune response to COVID-19 for different ages after mild infection. In this cohort of 252 family clusters with COVID-19, the immune response persisted until 12 months after infection in all age groups, with significantly higher antibody peaks for younger…
FDA recommends updating boosters to target Omicron
Editor's Note The Food and Drug Administration’s (FDA’s) Vaccines and Related Biological Products Advisory Committee on June 28 recommended updating the composition of COVID-19 booster vaccines to target the Omicron variant. The Committee noted that booster doses consisting of an Omicron monovalent or bivalent vaccine could improve neutralizing antibody responses…
Newer COVID-19 subvariants show substantial escape from vaccination, previous infection immunity
Editor's Note In a letter published in the New England Journal of Medicine, researchers at Beth Israel Deaconess Medical Center, Boston, report that the three Omicron subvariants (BA.2.12.1, BA.4, and BA.5) currently dominant in the US substantially escape neutralizing antibodies induced by both vaccination and previous COVID-19 infection. The researchers…
CDC lifts pre-departure COVID-19 testing for international travelers
Editor's Note The Centers for Disease Control and Prevention (CDC) on June 10 announced that it will no longer require international travelers to have a negative COVID-19 test before flying to the US, effective June 12. The CDC continues to recommend that travelers flying to the US get tested as…
Protection, waning of immunity to COVID-19 after infection, vaccination
Editor's Note This Israeli study finds that individuals previously infected with COVID-19, regardless of whether they had been vaccinated, had more protection against reinfection than those who were vaccinated (Pfizer-BioNTech vaccine) but previously uninfected. Among the findings for the number of COVID-19 cases per 100,000 person days since vaccination or…
