Editor's Note This Israeli study finds that antibody levels were associated with protection against infection with the COVID-19 Omicron variant in vaccinated healthcare workers (HCWs). Participants included 2,310 HCWs who had received 3 or 4 doses of an mRNA COVID-19 vaccine. The odds of infection and substantial symptomatic disease caused…

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Editor's Note This Italian review and meta-analysis finds that the effectiveness of COVID-19 vaccines against Omicron and Delta variants rapidly wans over time. Of 799 original articles, 149 reviews, and 35 preprints identified, 40 studies were included in the analysis. Among the findings: Vaccine effectiveness of a primary vaccination cycle…

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Editor's Note This meta-analysis by researchers from Iran University of Medical Sciences, Tehran; Harvard Medical School, Boston; and Johns Hopkins University School of Medicine, Baltimore, finds a greater risk for Bell's palsy with COVID-19 infection, compared with COVID-19 vaccination. A total of 50 studies were included in the analysis with…

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Editor's Note This study by researchers from the University of Southern California, Los Angeles, finds substantial adverse maternal outcomes among pregnant patients with COVID-19 at delivery, during the early pandemic period. A total of 2,578,095 patients were analyzed. During the 9-month study period (April to December 2020), 45,425 pregnant patients…

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Editor's Note The Centers for Disease Control and Prevention (CDC), on March 29, updated its COVID-19 vaccination guidelines to say that one dose of the bivalent booster is all that is recommended at this time, even for those who were last vaccinated more than 6 months ago. The CDC notes…

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Editor's Note The World Health Organization, on March 28, announced the revision of it’s guidance for prioritizing the use of COVID-19 vaccines after the meeting of its Strategic Advisory Group of Experts on Immunization (SAGE). The guidance was revised to reflect that much of the population has either been vaccinated…

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Editor's Note This German study finds that expectations and prior experiences were associated with increased adverse effect reports in individuals receiving their second COVID-19 vaccinations. Researchers collected data from 1,678 individuals receiving Pfizer BioNTech and Moderna mRNA vaccines. Severe adverse effect reports were higher in those: expecting a lower benefit…

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Editor's Note California health officials, on March 3, announced plans to relax guidance on masking in healthcare and other indoor high-risk settings and to end vaccination requirements for healthcare workers, effective April 3, the March 3 Los Angeles Times reports. Also, starting March 13, those who test positive for COVID-19…

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Editor's Note This systematic review and meta-analysis by researchers at the University of Washington, Seattle, finds that natural immunity provided by past COVID-19 infection offers strong protection against reinfection and severe disease for at least 40 weeks. The analysis included 65 studies from 19 countries. Among the findings: For those…

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Editor's Note In a press release published on February 15, Moderna announced that will remain “committed to ensuring” people in the US will have access to its COVID-19 vaccines even after the COVID-19 Public Health Emergency ends on May 11, 2023, regardless of people’s ability to pay. The public health…

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