Editor's Note According to results from a randomized trial, titled KEYNOTE-689, adding pembrolizumab (Keytruda) to surgery and standard adjuvant therapy significantly prolongs event-free survival (EFS) in patients with resectable, locally advanced head and neck squamous cell carcinoma (HNSCC), MedPage Today April 28 reports. Experts are calling the findings a major…

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Editor's Note Research published in Nature reveals that DNA damage caused by colibactin-producing gut bacteria is far more prevalent in younger patients with colorectal cancer, NBC News reports, suggesting a key factor behind the disturbing rise in cases among people under 40.  According to the April 23 article, researchers from…

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Editor's Note Current US CT scan practices could lead to approximately 103,000 future cancers—nearly 5% of all new annual diagnoses—if utilization and radiation dosing patterns persist, according to a risk modeling study published April 14 in JAMA Internal Medicine. Authors emphasized that although CT is often lifesaving, its risks are…

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Editor's Note The Government Accountability Office (GAO) has called on the Department of Health and Human Services (HHS) to implement a formal mechanism for coordinating efforts to address ongoing drug shortages, which continue to jeopardize patient care nationwide. In a report released April 9, 2025, the GAO highlighted the critical…

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Editor's Note Pregnancy-related deaths in the US rose sharply from 2018 to 2022, with rates 3.8 times higher among American Indian and Alaska Native women and 2.8 times higher among non-Hispanic Black women than among White women, according to a new study published April 9 in JAMA Network Open. Researchers…

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Editor's Note Cannabis users may require higher doses of anesthetics during sedation and experience worse physical and psychological symptoms during cancer treatment, according to an April 7 announcement from the University of Oklahoma (OU). Publishing in the journal Gastrointestinal Endoscopy, a multidisciplinary team of university researchers found that cannabis users…

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Editor's Note Machine learning (ML) models designed to predict patient mortality are falling short when it comes to identifying severe injuries that could lead to death, according to a March 27 report in TechTarget. The article focuses on research published in Nature Communications Medicine found that ML mortality prediction models…

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Editor's Note Subtle risk factors—such as low BMI and hidden tumors—could lead to unexpected airway management difficulties, according to research published on March 17 in Nature: Scientific Reports. The case-control study analyzed 672 surgical patients who required endotracheal intubation between 2015 and 2020. Researchers compared 168 patients who experienced difficult…

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Editor's Note A wearable smart t-shirt that remotely monitors vital signs helped patients go home earlier and feel safer after robot-assisted urological cancer surgery, according to a March 21 article in Medical Xpress. The article details a pilot study, presented at the European Association of Urology Congress in Madrid, Spain,…

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Editor's Note Surgeons at Northwestern Medicine have performed the first U.S. case of resection and partial liver transplantation with delayed total hepatectomy (RAPID) to treat metastatic colorectal cancer, according to a March 18 article in Healio. The procedure, which allows a transplanted liver segment to grow before fully replacing a…

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