Editor's Note The US Food & Drug Administration (FDA) has approved immunotherapy durvalumab for perioperative treatment of resectable non-small cell lung cancer (NSCLC), according to an August 15 announcement. The approval is for durvalumab (Imfinzi, AstraZeneca) in combination with platinum-based chemotherapy as a neoadjuvant treatment, followed by durvalumab alone as…

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Editor's Note A post hoc analysis of the SCOT phase 3 randomized clinical trial reveals that initiating adjuvant chemotherapy more than 6 weeks after surgery is linked to worse disease-free survival (DFS) in patients with high-risk stage II and stage III colorectal cancer. Published June 12 in JAMA Surgery, the…

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Editor's Note An electronic health record (EHR)-based nudge could significantly reduce low-value axillary surgeries in older women with early-stage breast cancer, researchers reported July 17 in JAMA Surgery. Conducted across eight clinical settings, the initiative significantly cut the rates of low-value sentinel lymph node biopsies (SLNB) by nearly 50% over…

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Editor's Note A Massachusetts man, Marty Kedian, regained his voice after a pioneering larynx transplant at the Mayo Clinic in Arizona, The Associated Press (AP) reported July 9. According to the article, Kedian is only the third person in the U.S. to receive a total larynx transplant and the first…

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Editor's Note Early-onset colorectal cancer (EO-CRC), diagnosed before age 50, is increasing in incidence worldwide. Despite existing postoperative colonoscopy surveillance strategies, the optimal intervals for EO-CRC patients are unclear due to limited long-term data. This study, titled “Early-onset Colorectal Cancer Patients Do Not Require Shorter Intervals for Post-surgical Surveillance Colonoscopy”…

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Editor's Note In a recent study, an artificial intelligence (AI) system detected more clinically significant prostate cancers and fewer indolent cancers than human radiologists reading MRIs, MedPage today reported June 13. The MedPage report covers a study published in Lancet Oncology that, according to researchers, “provided evidence that AI systems,…

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When it comes to the adoption of artificial intelligence (AI) in medicine, radiology is leading the charge. As of May 13, 2024, the US Food and Drug Administration (FDA) had approved nearly 900 AI- and machine learning (ML)-enabled devices, and the vast majority of them are in radiology. One example…

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Editor's Note A pair of immunotherapy drugs administered before surgery significantly diminished tumor size without serious safety concerns in patients with mismatch repair-deficient (dMMR) colorectal cancer, according to a study published in the New England Journal of Medicine. Healthline reported the news June 8. Constituting 10-15% of cases, dMMR cancer…

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Editor's Note Robotic liver surgery can be performed safely as an outpatient procedure, according to findings from the City of Hope cancer research organization in Duarte, California. According to a June 10 press release, the study analyzed data of 307 patients who underwent outpatient robotic liver surgery (defined as requiring…

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Editor's Note In esophageal cancer, combining preoperative and postoperative chemotherapy lead to better outcomes, fewer deaths, and higher likelihood of complete tumor regression than preoperative chemotherapy alone, according to a randomized clinical trial. US News and World Report reported the news June 4. Led by Dr. Jens Hoeppner from the…

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