November 15, 2022

COVID-19 symptoms 2 years after infection in hospitalized vs nonhospitalized patients

By: Judy Mathias

Editor's Note

This study from Spain finds that 59.7% of hospitalized and 67.5% of nonhospitalized COVID-19 patients had at least one symptom 2 years after infection.

Of 360 hospitalized and 308 nonhospitalized COVID-19 patients analyzed, fatigue (161 vs 147), pain (129 vs 92), and memory loss (72 vs 49) were the most prevalent post-COVID-19 symptoms at 2 years. No significant differences in post-COVID-19 symptoms were found between hospitalized and nonhospitalized patients.

The number of preexisting comorbidities was associated with post-COVID-19 fatigue (Odds Ratio [OR] 1.93) and dyspnea (OR 1.91) in hospitalized patients. The number of preexisting comorbidities (OR 3.75) and the number of symptoms at onset of illness (OR 3.84) were associated with post-COVID-19 fatigue in nonhospitalized patients.

The similar rates of post-COVID-19 symptoms in hospitalized and nonhospitalized patients supports that long COVID will require specific attention independently of whether the patient was hospitalized or not, the researchers say.

JAMA (healthcare publication) Network logo


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