Editor's Note According to results from a randomized trial, titled KEYNOTE-689, adding pembrolizumab (Keytruda) to surgery and standard adjuvant therapy significantly prolongs event-free survival (EFS) in patients with resectable, locally advanced head and neck squamous cell carcinoma (HNSCC), MedPage Today April 28 reports. Experts are calling the findings a major…
Editor's Note Perioperative immunotherapy is reshaping treatment strategies for early-stage non-small cell lung cancer (NSCLC) without actionable mutations, according to Dr. Roy S. Herbst of Yale Cancer Center. In a recent interview with OncLive, the oncology expert highlighted the promise of neoadjuvant and adjuvant therapies to improve outcomes for these…
Editor's Note The US Food & Drug Administration (FDA) has approved immunotherapy durvalumab for perioperative treatment of resectable non-small cell lung cancer (NSCLC), according to an August 15 announcement. The approval is for durvalumab (Imfinzi, AstraZeneca) in combination with platinum-based chemotherapy as a neoadjuvant treatment, followed by durvalumab alone as…
Editor's Note A pair of immunotherapy drugs administered before surgery significantly diminished tumor size without serious safety concerns in patients with mismatch repair-deficient (dMMR) colorectal cancer, according to a study published in the New England Journal of Medicine. Healthline reported the news June 8. Constituting 10-15% of cases, dMMR cancer…
Editor's Note Steven Rosenberg, MD, PhD, chief of the Surgery Branch at the Center for Cancer Research at the National Cancer Institute, part of the National Institutes of Health (NIH), and a pioneer in the development of immunotherapy to fight cancer, was awarded the National Medal of Technology and Innovation.…