Editor's Note According to results from a randomized trial, titled KEYNOTE-689, adding pembrolizumab (Keytruda) to surgery and standard adjuvant therapy significantly prolongs event-free survival (EFS) in patients with resectable, locally advanced head and neck squamous cell carcinoma (HNSCC), MedPage Today April 28 reports. Experts are calling the findings a major…

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Editor's Note Research published in Nature reveals that DNA damage caused by colibactin-producing gut bacteria is far more prevalent in younger patients with colorectal cancer, NBC News reports, suggesting a key factor behind the disturbing rise in cases among people under 40.  According to the April 23 article, researchers from…

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Editor's Note Current US CT scan practices could lead to approximately 103,000 future cancers—nearly 5% of all new annual diagnoses—if utilization and radiation dosing patterns persist, according to a risk modeling study published April 14 in JAMA Internal Medicine. Authors emphasized that although CT is often lifesaving, its risks are…

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Editor's Note Some patients with early-stage breast cancer who achieve a complete response to pre-surgical chemotherapy and radiation may safely avoid surgery, according to a March 27 announcement from The University of Texas MD Anderson Cancer Center. The report details a Phase II trial, published in JAMA Oncology, finding that…

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Editor's Note Surgeons at Northwestern Medicine have performed the first U.S. case of resection and partial liver transplantation with delayed total hepatectomy (RAPID) to treat metastatic colorectal cancer, according to a March 18 article in Healio. The procedure, which allows a transplanted liver segment to grow before fully replacing a…

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Editor's Note A newly developed predictive model offers healthcare professionals a dynamic tool to assess the risk of nosocomial infections (NIs) in patients following colon cancer surgery, potentially improving early intervention strategies. Published February 27 in Frontiers in Oncology, the study introduces a nomogram—a statistical model that visualizes key risk…

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Editor's Note New consensus recommendations from the US Multi-Society Task Force on Colorectal Cancer (MSTFCRC) set a 90% adequacy benchmark for bowel preparation in colonoscopy, reinforcing the role of preparation in ensuring accurate screenings and reducing the risk of missed lesions. As detailed in a March 4 joint press release…

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Editor's Note A new genetic testing tool could allow surgeons to accurately identify cancer cells in real time during brain surgery, potentially improving surgical outcomes and reducing cancer recurrence, NYU Langone Health System announced.  According to a February 25 press release, the Ultra-Rapid droplet digital PCR (UR-ddPCR) technique identifies cancer…

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Editor's Note Individuals with negative colonoscopy screening (NCS) results face significantly lower long-term risk of colorectal cancer (CRC) incidence and mortality, suggesting the recommended 10-year rescreening interval could be safely extended for low-risk populations, according to a study published in JAMA Oncology. Healio reported on the results January 15. As…

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Editor's Note A new international study reports low rates of local recurrence, radionecrosis, and leptomeningeal disease in patients receiving neoadjuvant stereotactic radiosurgery (SRS) before brain metastases resection, Medscape Medical News reported January 6. Published in Radiotherapy and Oncology, the analysis included 179 patients with 189 brain metastases treated at nine…

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