Drug that makes tumors glow is transforming cancer surgery
Editor's Note A new drug is giving surgeons a sharper view of cancer in the OR and helping preserve healthy tissue, Fast Company August 28 reports. Cytalux is an FDA-approved fluorescent agent that makes cancer cells glow green under infrared light, allowing surgeons to spot and remove malignant lesions with…
UC Davis secures $2M to study bone health in prostate cancer, prevent post-injury arthritis
Editor's Note The UC Davis Department of Orthopaedic Surgery has received more than $2.2 million in Department of Defense funding for two research projects addressing bone health in prostate cancer and preventing arthritis after joint injuries, a UC Davis Health July 15 news release reports. The larger grant, $1.8 million,…
Breast cancer surgery delays tied to higher upstaging, faster tumor growth
Editor's Note Each month of delay between breast cancer diagnosis and surgery raises the likelihood of tumor upstaging, nodal spread, and in vivo tumor growth, according to a national database analysis published in Annals of Surgical Oncology on July 23. The researchers reviewed records from more than 1 million patients…
Study: 3D-printed models improve shared decision-making in colorectal surgery
Editor's Note Research shows using 3D-printed anatomical models during preoperative counseling can improve patients’ involvement in shared decision-making (SDM) and reduced anxiety ahead of colorectal surgery, although only the improvement in SDM met the study’s threshold for clinical significance. Published June 3 in JAMA Network Open, the single-center trial included…
Study: Blood test detects colorectal cancer but misses most precancerous polyps
Editor's Note A new blood test shows promise in detecting colorectal cancer—the second leading cause of cancer deaths in the US—but was less effective at identifying precancerous polyps, according to a June 2 announcement from Kaiser Permanente. Not yet approved by the US Food and Drug Administration, the test is…
Study: Simple hysterectomy survival comparable to more radical procedures in early cervical cancer
Editor's Note Simple hysterectomy provides similar long-term survival outcomes to modified radical or radical hysterectomy for patients with low-risk, early-stage cervical cancer, according to a large cohort study published May 15 in JAMA Network Open. Consistent with prior research, the findings add to the growing body of evidence supporting conservative…
Study: Shorter radiation schedule matches safety of standard prostate cancer treatment
Editor's Note New research shows postoperative prostate cancer radiation delivered via stereotactic body radiotherapy (SBRT)—which includes just five high-dose sessions—appears as safe and tolerable as weeks-long conventional treatment. Medical Xpress reported on the findings May 15. Led by by UCLA’s Jonsson Comprehensive Cancer Center and published in JAMA Oncology, the…
Study: Fewer men undergo unnecessary prostate cancer surgery amid rise in active surveillance
Editor's Note Prostate cancer surgeries for low-risk patients have plummeted since 2010, signaling major progress in reducing overtreatment, according to an April 29 announcement from the University of Michigan. University researchers reportedly found that the proportion of men undergoing prostatectomy for Grade Group 1 prostate cancer—the lowest-risk category—dropped more than…
Pembrolizumab sets new standard in advanced head and neck cancer surgery, trial shows
Editor's Note According to results from a randomized trial, titled KEYNOTE-689, adding pembrolizumab (Keytruda) to surgery and standard adjuvant therapy significantly prolongs event-free survival (EFS) in patients with resectable, locally advanced head and neck squamous cell carcinoma (HNSCC), MedPage Today April 28 reports. Experts are calling the findings a major…
Study: Colibactin-producing gut bacteria fuel colorectal cancer surge
Editor's Note Research published in Nature reveals that DNA damage caused by colibactin-producing gut bacteria is far more prevalent in younger patients with colorectal cancer, NBC News reports, suggesting a key factor behind the disturbing rise in cases among people under 40. According to the April 23 article, researchers from…
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