Study: 3D-printed models improve shared decision-making in colorectal surgery
Editor's Note Research shows using 3D-printed anatomical models during preoperative counseling can improve patients’ involvement in shared decision-making (SDM) and reduced anxiety ahead of colorectal surgery, although only the improvement in SDM met the study’s threshold for clinical significance. Published June 3 in JAMA Network Open, the single-center trial included…
Study: Blood test detects colorectal cancer but misses most precancerous polyps
Editor's Note A new blood test shows promise in detecting colorectal cancer—the second leading cause of cancer deaths in the US—but was less effective at identifying precancerous polyps, according to a June 2 announcement from Kaiser Permanente. Not yet approved by the US Food and Drug Administration, the test is…
Study: Simple hysterectomy survival comparable to more radical procedures in early cervical cancer
Editor's Note Simple hysterectomy provides similar long-term survival outcomes to modified radical or radical hysterectomy for patients with low-risk, early-stage cervical cancer, according to a large cohort study published May 15 in JAMA Network Open. Consistent with prior research, the findings add to the growing body of evidence supporting conservative…
Study: Shorter radiation schedule matches safety of standard prostate cancer treatment
Editor's Note New research shows postoperative prostate cancer radiation delivered via stereotactic body radiotherapy (SBRT)—which includes just five high-dose sessions—appears as safe and tolerable as weeks-long conventional treatment. Medical Xpress reported on the findings May 15. Led by by UCLA’s Jonsson Comprehensive Cancer Center and published in JAMA Oncology, the…
Study: Fewer men undergo unnecessary prostate cancer surgery amid rise in active surveillance
Editor's Note Prostate cancer surgeries for low-risk patients have plummeted since 2010, signaling major progress in reducing overtreatment, according to an April 29 announcement from the University of Michigan. University researchers reportedly found that the proportion of men undergoing prostatectomy for Grade Group 1 prostate cancer—the lowest-risk category—dropped more than…
Pembrolizumab sets new standard in advanced head and neck cancer surgery, trial shows
Editor's Note According to results from a randomized trial, titled KEYNOTE-689, adding pembrolizumab (Keytruda) to surgery and standard adjuvant therapy significantly prolongs event-free survival (EFS) in patients with resectable, locally advanced head and neck squamous cell carcinoma (HNSCC), MedPage Today April 28 reports. Experts are calling the findings a major…
Study: Colibactin-producing gut bacteria fuel colorectal cancer surge
Editor's Note Research published in Nature reveals that DNA damage caused by colibactin-producing gut bacteria is far more prevalent in younger patients with colorectal cancer, NBC News reports, suggesting a key factor behind the disturbing rise in cases among people under 40. According to the April 23 article, researchers from…
Study: CT scan radiation could drive 5% of future cancer cases
Editor's Note Current US CT scan practices could lead to approximately 103,000 future cancers—nearly 5% of all new annual diagnoses—if utilization and radiation dosing patterns persist, according to a risk modeling study published April 14 in JAMA Internal Medicine. Authors emphasized that although CT is often lifesaving, its risks are…
Study: Early-stage breast cancer surgery may not be necessary after chemo, radiation
Editor's Note Some patients with early-stage breast cancer who achieve a complete response to pre-surgical chemotherapy and radiation may safely avoid surgery, according to a March 27 announcement from The University of Texas MD Anderson Cancer Center. The report details a Phase II trial, published in JAMA Oncology, finding that…
Novel liver transplant technique offers new hope for colorectal cancer patients
Editor's Note Surgeons at Northwestern Medicine have performed the first U.S. case of resection and partial liver transplantation with delayed total hepatectomy (RAPID) to treat metastatic colorectal cancer, according to a March 18 article in Healio. The procedure, which allows a transplanted liver segment to grow before fully replacing a…
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