Study: Blood test detects colorectal cancer but misses most precancerous polyps
Editor's Note A new blood test shows promise in detecting colorectal cancer—the second leading cause of cancer deaths in the US—but was less effective at identifying precancerous polyps, according to a June 2 announcement from Kaiser Permanente. Not yet approved by the US Food and Drug Administration, the test is…
Study: Shorter radiation schedule matches safety of standard prostate cancer treatment
Editor's Note New research shows postoperative prostate cancer radiation delivered via stereotactic body radiotherapy (SBRT)—which includes just five high-dose sessions—appears as safe and tolerable as weeks-long conventional treatment. Medical Xpress reported on the findings May 15. Led by by UCLA’s Jonsson Comprehensive Cancer Center and published in JAMA Oncology, the…
Pembrolizumab sets new standard in advanced head and neck cancer surgery, trial shows
Editor's Note According to results from a randomized trial, titled KEYNOTE-689, adding pembrolizumab (Keytruda) to surgery and standard adjuvant therapy significantly prolongs event-free survival (EFS) in patients with resectable, locally advanced head and neck squamous cell carcinoma (HNSCC), MedPage Today April 28 reports. Experts are calling the findings a major…
Study: Colibactin-producing gut bacteria fuel colorectal cancer surge
Editor's Note Research published in Nature reveals that DNA damage caused by colibactin-producing gut bacteria is far more prevalent in younger patients with colorectal cancer, NBC News reports, suggesting a key factor behind the disturbing rise in cases among people under 40. According to the April 23 article, researchers from…
Study: Starting adjuvant chemotherapy more than 6 weeks after surgery worsens colorectal cancer survival
Editor's Note A post hoc analysis of the SCOT phase 3 randomized clinical trial reveals that initiating adjuvant chemotherapy more than 6 weeks after surgery is linked to worse disease-free survival (DFS) in patients with high-risk stage II and stage III colorectal cancer. Published June 12 in JAMA Surgery, the…
Study reveals puzzling paradox on bilateral mastectomy, breast cancer survival outcomes
Editor's Note Medical professionals have long accepted that bilateral mastectomy does not improve survival outcomes for breast cancer patients. However, a study published in JAMA Oncology reveals a puzzling finding: Those who develop a second cancer in the other breast have a higher risk of death. As detailed in a…
Cancer diagnoses rise; shift to younger demographic
Editor's Note: Although overall mortality from cancer continues to decline, diagnoses continue to increase and have shifted from older to middle-aged adults. These are among the conclusions of the latest report from the American Cancer Society, which was published in CA: A Cancer Journal for Clinicians. “Among adults younger than 50…
Associations of aerobic, muscle-strengthening activities with mortality
Editor's Note This study led by researchers in Spain examines the optimal combination of moderate aerobic physical activities, vigorous aerobic physical activity, and muscle-strengthening activity to reduce all-cause cardiovascular and cancer mortality. Using data from the US National Health Interview Survey, a total of 500,705 participants were included in the…
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