Editor's Note The US Food and Drug administration approved Zevtera for treating Staphylococcus aureus bacteremia (SAB) bloodstream infections, which are often acquired in healthcare settings. In the April 3 announcement, the agency notes the new antibiotic Zevtera (ceftobiprole medocaril sodium for injection) is effective for SAB-infected patients with right-sided infective…

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Editor's Note Findings published March 4 in Jama Network show that preoperative urine culture is a low-value intervention for most surgical patients and should be de-implemented. Despite guidelines to the contrary from Infectious Diseases Society of America and the American College of Physicians, preoperative urine testing and antibiotic treatment persists…

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Editor's Note: A point-of-care, antimicrobial coating for orthopedic implants could soon make implant-associated infections a problem of the past, UCLA Health reported on January 3. Developed by two UCLA surgeons, the coating is designed to kill or slow the spread of micro-organisms in order to prevent post-surgical infections. According to…

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Editor's Note Widespread antibiotic resistance globally has meant that drugs used to treat common infections in children and babies are no longer effective, according to a new study published on October 31 by Science Direct. The study found that a number of antibiotics recommended by the World Health Organization (WHO)…

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Editor's Note Pfizer alerted the Food and Drug Administration (FDA) on June 12 that its supply of two forms of injectable penicillin—Bicillin L-A and Bicillin C-R—may run out by the end of this month, the June 13 The Hill reports. Pfizer cited a combination of factors for the shortage, including…

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Editor's Note The Society for Healthcare Epidemiology of America (SHEA) has updated the Strategies to Prevent Surgical Site Infection in Acute Care Hospitals, which was published in 2014. The update highlights practical recommendations designed to assist acute-care hospitals in implementing and prioritizing their surgical site infection (SSI) prevention efforts. Among…

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Editor's Note This update to the 2014 "Strategies to Prevent Surgical Site Infections in Acute Care Hospitals" recommends that antibiotics be discontinued after a patient’s incision has been closed in the OR, even if drains are present. The expert panel members writing the update add that continuing antibiotics after closure…

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Editor's Note The Joint Commission on June 22 announced a new “R3 Report—Issue 35: New and Revised Requirements for Antibiotic Stewardship,” which details the rationale and references behind new and revised requirements to optimize the use of antibiotics, effective January 1, 2023. The requirements include 12 new and revised elements…

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Editor's Note This study by researchers at the Pennsylvania State University College of Medicine, Hershey, finds that patients who had a penicillin allergy carried a higher risk for negative outcomes with COVID-19 than those without the allergy. This analysis included 13,183 adults with COVID-19 and a penicillin allergy and 13,183…

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Editor's Note In this case study, craniofacial surgeons from Brazil describe their experience with a 28-year-old COVID-19-positive man who developed orbital cellulitis, requiring surgical intervention. A few weeks before, the man had a mild illness with fatigue and loss of smell and taste. He didn’t seek medical care until he…

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