February 12, 2024

Mood changes, sleep quality improve after primary hyperparathyroidism surgery

Editor's Note

Benefits to mood and sleep should be considered in preoperative consultations with patients with primary hyperparathyroidism, according to a study published February 12 in the journal Surgery. The researchers’ recommendation reportedly departs from the latest recommendations published according to the primary hyperparathyroidism surgical consensus, which exclude these neuropsychological symptoms.

Their conclusion is based on a prospective case-control study of 49 patients who underwent parathyroidectomy. Compared to an age- and sex-matched control group, depression scores indicated by The Beck questionnaire decreased significantly, including after 1 year. For sleep quality, measured by the Pittsburgh Sleep Quality Index, the researchers observed no differences 3 months after the intervention but significant differences in daytime disfunction 3 and 12 months after surgery.

“Mood changes and sleep quality improve after primary hyperparathyroidism surgery, although at different postoperative times, with this improvement being more pronounced in mood,” the researchers write. “This assessment should be taken into account in the preoperative consultation of patients with primary hyperparathyroidism.”


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