Editor's Note Glucagon-like peptide-1 (GLP-1) receptor agonists may offer orthopedic patients with obesity and type 2 diabetes a powerful tool for preoperative weight loss and potential disease modification, according to a July 10 review article in The Journal of Bone and Joint Surgery. However, the agents carry perioperative risks that…

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Editor's Note Research shows using GLP-1 receptor agonists both before and after bariatric surgery is associated with greater total weight loss than surgery alone, according to a July 13 article in MedPage Today. The article focuses on a retrospective analysis of 568 patients presented at ENDO 2025, the annual meeting…

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Editor's Note Bariatric surgery produced five times greater weight loss than GLP-1 medications in a new study of over 51,000 patients with obesity, according to a June 18 article from Fox News. The retrospective study, funded by the NIH and conducted by researchers at NYU Langone Health and NYC Health…

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Editor's Note Patients taking GLP-1 receptor agonists (GLP-1 RAs) do not need to discontinue these medications before undergoing anesthesia but should follow extended preoperative fasting protocols to reduce aspiration risk, according to a June 5 article in Medscape. As detailed in the article, this recommendation comes from a new multidisciplinary…

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Editor's Note Patients taking SGLT2 inhibitors face a higher risk of postoperative euglycemic ketoacidosis (eKA) but experience fewer acute kidney injuries and deaths after surgery, according to an April 30 article in Medical Xpress. The article focuses on new research published in JAMA Surgery. Led by researchers at the University…

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Editor's Note Bariatric surgery improves survival and appears cost-effective over a decade for patients with obesity and compensated cirrhosis, according to an April 18 report in Healio. The findings, based on an analysis published in JAMA Surgery, suggest that bariatric surgery could fill a crucial gap in care for this…

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Editor's Note Taking GLP-1 receptor agonists before anesthesia increases the risk of residual gastric contents, but evidence is lacking for a corresponding increase in perioperative pulmonary aspiration risk, according research published April 15 in the journal Anaesthesia. The systematic review and meta-analysis analyzed 28 observational studies involving over 466,000 patients…

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Editor's Note The widespread adoption of GLP-1 weight-loss medications like Ozempic and Wegovy could put revenue at risk across multiple service lines, according to a March 11 article in Becker’s Hospital Review. As a result, hospitals and ambulatory surgery centers (ASCs) face critical questions about how to adapt. The article…

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Editor's Note Preoperative use of GLP-1 receptor agonists was not significantly associated with an increased risk of aspiration pneumonia or acute respiratory failure after surgery, according to a March 4 report in MedPage Today. The article focuses on a retrospective cohort study of over 366,000 surgical patients found no meaningful…

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Editor’s Note Preoperative use of sodium-glucose cotransporter 2 inhibitors (SGLT2i) does not increase the risk of postoperative diabetic ketoacidosis (DKA) in patients undergoing emergency surgery, according to a study published February 19 in JAMA Surgery. These findings challenge the current FDA recommendation to withhold SGLT2i medications for at least three…

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