Tag: clinical trial

Targeted intraoperative radiation slashes pancreatic cancer recurrence to 5%

Editor's Note A Johns Hopkins team is reporting unprecedented success in preventing pancreatic cancer recurrence by combining pre-surgical and intraoperative radiation focused on a key anatomical area near the pancreas, News Medical Life Sciences October 30 reports. Citing a Johns Hopkins Medicine preliminary study, this approach reportedly reduced recurrence around…

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By: Tarsilla Moura
November 5, 2025
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Minimally invasive TAVR matches open-heart surgery in 7-year outcomes for aortic valve replacement

Editor's Note A Phase III clinical trial comparing transcatheter aortic valve replacement (TAVR) with traditional open-heart surgery found no significant differences in key health outcomes 7 years after treatment, Cedars-Sinai October 27 reports. The international PARTNER 3 trial, led by Raj Makkar, MD, and published in The New England Journal…

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By: Tarsilla Moura
November 4, 2025
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UCSF surgeons spotlight innovation, perioperative research at national surgical conference

Editor's Note University of California San Francisco (UCSF) surgeons and researchers presented a wide range of original work at the American College of Surgeons’ 2025 Clinical Congress in Chicago, held October 4–7. According to an October 7 article published by UCSF, the meeting featured topics from perioperative opioid stewardship and…

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By: Tarsilla Moura
October 20, 2025
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Higher MAP targets in acute spinal cord injury show no neurologic benefit, more complications

Editor's Note Early blood pressure augmentation did not improve neurologic outcomes and was linked to more complications, according to a JAMA Network study published on September 18. In this multicenter randomized clinical trial at 13 US trauma centers, 92 adults with acute cervical or thoracic spinal cord injury were assigned…

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By: Tarsilla Moura
October 1, 2025
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Keeping sensory aids in place during surgery reduces delirium risk in older hip fracture patients

Editor's Note Allowing older surgical patients to keep dentures, glasses, and hearing aids until anesthesia and restoring them immediately afterward significantly lowered postoperative delirium (POD) rates, according to a study published in BMC Geriatrics on August 30. The prospective before-and-after trial followed patients aged 70 and older undergoing hip fracture…

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By: Tarsilla Moura
September 25, 2025
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Minimally invasive ICH surgery evacuates clot fast but fails to improve 6-month outcomes

Editor's Note Minimally invasive surgery (MIS) with the Artemis Neuro Evacuation Device reduced hematoma volume efficiently and lowered serious adverse events but did not improve long-term disability or mortality compared with medical management in spontaneous supratentorial intracerebral hemorrhage (ICH), JAMA Neurology September 2 reports. The “MIND randomized clinical trial” enrolled…

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By: Tarsilla Moura
September 4, 2025
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Gait retraining eases knee osteoarthritis pain as effectively as medication, can delay knee surgery

Editor's Note A simple adjustment to walking style can relieve osteoarthritis pain as well as medication and may delay the need for knee surgery, according to a year-long clinical trial published in The Lancet Rheumatology and covered by The Independent on August 18. As detailed in the article, University of…

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By: Tarsilla Moura
September 3, 2025
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Drug that makes tumors glow is transforming cancer surgery

Editor's Note A new drug is giving surgeons a sharper view of cancer in the OR and helping preserve healthy tissue, Fast Company August 28 reports. Cytalux is an FDA-approved fluorescent agent that makes cancer cells glow green under infrared light, allowing surgeons to spot and remove malignant lesions with…

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By: Tarsilla Moura
September 2, 2025
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Study finds no link between long-standing preprocedural fasting and aspiration pneumonia risk

Editor's Note Loosening fasting policies before surgery does not increase the risk of post-surgical aspiration, also known as aspiration pneumonia, according to a systematic review and meta-analysis published in the journal Surgery in August 2025. The researchers analyzed 17 studies published between 2016 and 2023, including randomized clinical trials and…

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By: Tarsilla Moura
August 25, 2025
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Robot surgery spans continents in FDA-backed trial

Editor's Note A Florida-based surgeon successfully performed a prostate cancer surgery on a patient in Angola—7,000 miles away—marking a major milestone in transcontinental robotic telesurgery, according to a June 17 article from ABC News. The procedure, conducted by Dr. Vipul Patel of Advent Health’s Global Robotic Institute, is reportedly the…

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By: Matt Danford
June 24, 2025
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