Tag: clinical trial

Neurosurgery trial: Early evacuation improves long-term hemorrhage outcomes

Editor's Note Medical management care with evacuation surgery could yield better 180-day outcomes than without in patents treated within 24 hours for acute intracerebral hemorrhage, according to study results covered in an April 10 MedPage Today report. The ENRICH (Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ICH)) trial is a multicenter,…

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By: Matt Danford
April 18, 2024
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Study recommends against polyhexanide wound irrigation during open abdominal surgery

Editor's Note Although intraoperative wound irrigation is a common practice worldwide for preventing surgical site infections, a recent study suggests irrigation with polyhexanide solution should not be recommended as standard clinical practice in open clean-contaminated surgical procedures. Published February 21 in Jama Surgery, the study cautions that additional trials are…

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By: Matt Danford
March 28, 2024
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Moderna mRNA RSV vaccine proves effective for older adults

Editor’s note Moderna’s mRNA-based RSV vaccine is effective in preventing RSV-associated lower-respiratory tract disease in adults aged 60 an older, according to randomized phase II-III trial results published December 14 in The New England Journal of Medicine. Results also confirmed the safety of a single dose of the vaccine, researchers…

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By: Matt Danford
December 22, 2023
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Senate appoints oncologist, cancer researcher as NIH director

Editor's Note The US Senate has appointed Monica Bertagnolli, MD, as the new director of the National Institutes of Health (NIH), the agency’s first permanent leader in nearly 2 years and the second woman to hold the post. She is expected to face significant scrutiny from lawmakers, Chief Healthcare Executive…

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By: Brita Belli
November 17, 2023
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Concerted push for greater diversity in medical studies ongoing

Editor's Note Although Congress first required the National Institutes of Health to include more women and people of color in medical studies in 1993, progress has been slow until recently. Now, researchers are making a concerted effort to diversify medical studies, The Wall Street Journal (WSJ) November 16 reports.  According…

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By: Brita Belli
November 16, 2023
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Video laryngoscopy leads to higher success rates than direct laryngoscopy

Editor's Note Video laryngoscopy was found to lead to higher intubation success rates over direct laryngoscopy in critically ill adult patients, an August 2023 randomized controlled trial published by the The New England Journal of Medicine shows. The findings were consistent whether they were intubated in an emergency room or…

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By: Brita Belli
October 30, 2023
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Improving underrepresented patient participation in clinical trials: It matters who makes the request

Editor's Note In this investigative study done by the Boston Medical Center (BMC), patients were shown more likely to agree to participate in clinical studies when approached by research staff of the same race or ethnicity as them. The findings were published in JAMA Ophthalmology on October 19.  The study…

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By: Brita Belli
October 20, 2023
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Survival rates strong following low-risk cardiac surgery

Editor's Note A new study in the Annals of Thoracic Surgery finds that long-term survival rates are extremely promising for patients who receive low-risk isolated surgical aortic valve replacement (SAVR). The study, titled "Survival Following Surgical Aortic Valve Replacement in Low-Risk Patients: A Contemporary Trial Benchmark," was published on October…

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By: Brita Belli
October 18, 2023
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Limiting opioid medication did not negatively impact patients post-surgery

Editor's Note A 5-day limit on opioid pain medication prescriptions in Michigan did not negatively impact patient-reported pain levels or satisfaction, JAMA Network October 13 reports. The study, titled "Changes in surgical opioid prescribing and patient-reported outcomes after implementation of an insurer opioid prescribing limit," was published by JAMA Health…

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By: Brita Belli
October 16, 2023
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First nasal vaccine in development for deadly Strep A

Editor's Note A new nasal vaccine in development by Griffith University’s Institute for Glycomics in Australia could provide long-term protection against the deadly bacteria Streptococcus A (Strep A), Griffith University's Griffith News October 5 reports. Strep A causes 700 million human infections each year, and there are more than 500,000…

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By: Brita Belli
October 9, 2023
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