Tag: drugs

Report: Health system margins shrink as hospital revenue grows

Editor's Note Operating margins for health systems declined across the US in early 2025 even as hospitals reported steady revenue growth, according to a February 27 report from Strata Decision Technology. The median operating margin for U.S. health systems dropped to 1.0% in January, down from 2.1% in December, marking…

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By: Matt Danford
March 4, 2025
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Study: Prolonged general anesthesia linked to long-term cognitive decline

Editor's Note Prolonged exposure to general anesthesia during surgery contributes to long-term cognitive decline, affecting executive functioning, selective attention, mental speed, and information processing, according to a February 18 study published in the European Journal of Anaesthesiology. This prospective longitudinal cohort study followed 1,823 adults aged 25–84 in the Netherlands…

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By: Matt Danford
February 28, 2025
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Research highlights anesthesia provider knowledge gap on drug, hormonal contraceptive interactions

Editor's Note Insufficient awareness of drug interactions with hormonal contraceptives (HCs) among anesthesia providers could lead to unintended pregnancies and preventable health consequences, according to survey published in Anesthesia & Analgesia. Physician’s Weekly covered the news February 27. The article specifically cites sugammedex and aprepitant, both of which are widely…

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By: Matt Danford
February 28, 2025
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Study links intraoperative synthetic opioids, worse postoperative pain

Editor's Note Using powerful synthetic opioids remifentanil and sufentanil during surgery increases risk of patients suffering during recovery, according to a study in the journal Regional Anesthesia & Pain Medicine. HealthDay reported the news February 27. According to the article, researchers analyzed data from 971 patients who underwent surgery—37% orthopedic…

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By: Matt Danford
February 27, 2025
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Study: Prophylactic antibiotics reduce SSIs in pediatric cholecystectomy

Editor's Note A cohort study published February 24 in JAMA Pediatrics found that prophylactic antibiotics reduced the odds of surgical site infections (SSIs) by 72% in children undergoing cholecystectomy for uncomplicated cholelithiasis. However, extended-spectrum antibiotics offered no additional benefit over cefazolin, suggesting that simpler prophylaxis protocols could optimize outcomes while…

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By: Matt Danford
February 26, 2025
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Preoperative SGLT2i use does not raise DKA risk in emergency surgery

Editor’s Note Preoperative use of sodium-glucose cotransporter 2 inhibitors (SGLT2i) does not increase the risk of postoperative diabetic ketoacidosis (DKA) in patients undergoing emergency surgery, according to a study published February 19 in JAMA Surgery. These findings challenge the current FDA recommendation to withhold SGLT2i medications for at least three…

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By: Matt Danford
February 24, 2025
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Study identifies potential non-surgical treatment for inguinal hernias

Editor's Note Researchers at Northwestern University successfully reversed hernias in male mice and restored normal anatomy without surgical intervention, according to a February 5 university announcement. The study also found that human hernia tissue shared the same molecular characteristics observed in the mouse model, suggesting a similar biological mechanism. According…

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By: Matt Danford
February 19, 2025
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Criminalizing anesthesia errors has unintended consequences, experts warn

Editor's Note Treating unintended anesthesia errors as criminal acts could exacerbate workforce shortages, increase malpractice costs, and drive clinicians to defensive medicine, according to experts quoted in a January 15 report from Anesthesiology News. Instead, fostering a culture of safety and learning could more effectively reduce errors and improve patient…

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By: Matt Danford
February 5, 2025
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FDA approves new non-opioid analgesic

Editor's Note The FDA has approved Journavx (suzetrigine), a first-in-class non-opioid analgesic, for the treatment of moderate to severe acute pain in adults. According to the agency’s January 30 announcement, the drug targets sodium channels in the peripheral nervous system to block pain signals before they reach the brain, representing…

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By: Matt Danford
February 5, 2025
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Study: ERAS protocol reduces opioid use after cardiac surgery

Editor's Note Implementing a multimodal analgesia-based enhanced recovery after surgery (ERAS) protocol significantly reduced both intraoperative opioid administration and postoperative opioid prescriptions in cardiac surgery patients, according to a January 5 report in Anesthesiology News. The findings were presented at the 2024 International Anesthesia Research Society meeting by Montefiore-Einstein Center…

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By: Matt Danford
January 30, 2025
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