Research

Latest Issue of OR Manager
January 2021

Large US study confirms COVID-19 complications

Editor's Note This large US study of patients who contracted COVID-19 confirms and provides risk estimates for numerous complications of the disease. Using US health claims data of 70,288 patients who had a COVID-19-related healthcare visit between March 1 and April 30, 2020, researchers found that 53.4% were admitted to…

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By: Judy Mathias
December 8, 2020
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Durablity of response to COVID-19 mRNA-1273 vaccination

Editor's Note This study led by the National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, finds that vaccinations with mRNA-1273 (Moderna) have the potential to provide durable humoral immunity. This report describes immunogenicity data for mRNA-1273 at 119 days after the first vaccination and 90 days after the second…

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By: Judy Mathias
December 3, 2020
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Marine study shows COVID-19 transmission despite public health measures, strict quarantine

Editor's Note This study of 1,848 US Marine Corps recruits finds that despite social distancing, wearing masks, regular handwashing, and other public health measures including strict quarantine, recruits contracted COVID-19 and spread it to others, even though hardly any of them had symptoms. Study participants were told to isolate themselves…

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By: Judy Mathias
November 18, 2020
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Moderna announces 94.5% efficacy for COVID-19 vaccine

Editor's Note Moderna Inc (Cambridge, Massachusetts) on November 16 announced that its vaccine is 94.5% effective at preventing COVID-19. Their analysis of a 30,000-person trial (half received the vaccine and half received a placebo) finds that 90 of the 95 COVID-19 documented cases are in the placebo group. The Moderna announcement…

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By: Judy Mathias
November 16, 2020
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AI tool detects COVID-19 by listening to patients’ coughs

Editor's Note Researchers from the Massachusetts Institute of Technology, Cambridge, have developed an artificial intelligence (AI) tool that can detect COVID-19 by listening to patients’ coughs, regardless if they are symptomatic or not. To build the tool, the researchers solicited audio recordings of patients coughing and accompanying information about their…

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By: Judy Mathias
November 10, 2020
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Final report on Remdesivir study for treatment of COVID-19

Editor's Note The November 5 final report on data from this double-blind, randomized, placebo-controlled study of intravenous remdesivir in adults hospitalized with COVID-19 and lower respiratory tract infection shows that remdesivir was superior to placebo in shortening the time to recovery. A total of 1,062 patients were randomized to remdesivir…

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By: Judy Mathias
November 5, 2020
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Researchers use AI to diagnose COVID-19 in chest x-rays

Editor's Note Researchers from the University of Minnesota and M Health Fairview are using artificial intelligence (AI) to detect COVID-19 in chest x-rays of hospitalized patients. The researchers used 18,000 x-rays from COVID-19 patients and 100,000 x-rays from patients without the disease to develop and train an AI program to…

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By: Judy Mathias
October 21, 2020
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Faulty bronchoscope reprocessing raises risks of infection transmission

Preventing infection transmission has been a chief concern of healthcare leaders and staff striving to protect their patients and themselves from SARS-CoV-2, the virus that causes COVID-19. The virus poses an insidious threat that includes the possibility of bronchoscopy-associated transmission of COVID-19. Long before the pandemic, epidemiologist and researcher Cori…

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By: Judith M. Mathias, MA, RN
October 21, 2020
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Study finds lasting protection in patients who have recovered from COVID-19

Editor's Note This study led by researchers at the Massachusetts General Hospital and Harvard Medical School, Boston, finds that patients who survive serious COVID-19 infections have a long-lasting immune response against the virus. The study includes a cohort of case patients with known COVID-19 infection (343) and controls (1,548). Blood…

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By: Judy Mathias
October 15, 2020
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Study: Remdesivir vs placebo for COVID-19 treatment

Editor's Note In this double-blind, randomized, placebo-controlled study of IV remdesivir in adults hospitalized with COVID-19 and lower respiratory tract infection, remdesivir was found to be superior to placebo in shortening the time to recovery. A total of 1,062 patients were randomized to either remdesivir (541) or placebo (521). Remdesivir…

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By: Judy Mathias
October 13, 2020
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