In this preliminary uncontrolled case series of five critically ill COVID-19 and acute respiratory distress syndrome (ARDS) patients, administration of convalescent plasma containing neutralizing antibody was followed by improvement in their clinical status.
All five patients (age 36-65 years, 2 women and 3 men) were on mechanical ventilation, and all had received antiviral agents and methylprednisolone.
After plasma transfusion:
Of the five patients, three have been discharged (length of stay: 53, 51, and 55 days), and two are in stable condition at 37 days after plasma transfusion.
The findings require evaluation in clinical trials, the researchers note.Read More >>