The use of chlorhexidine and alcohol for preoperative skin preparation resulted in a significantly lower risk of surgical site infections (SSIs) after cesarean deliveries than iodine and alcohol in this study.
Those who had the chlorhexidine prep had a 4% infection rate, which is nearly half that of patients who had the iodine prep (7.3%).
The study included 1,147 patients who had cesarean deliveries at Barnes-Jewish Hospital in St Louis. This is the largest study comparing any two antiseptics at any surgical procedure, the authors note.
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