This study represents the first description of critically ill patients infected with SARS-CoV-2 in the US. These patients had a high rate of acute respiratory distress syndrome (ARDS) and a high risk of death, similar to patients in China.
A total of 21 patients with a mean age of 70 years were included. The majority were linked to exposures at a skilled nursing facility. Comorbidities were identified in 18 patients (86%), with chronic kidney disease and congestive heart failure the most common.
Mean onset of symptoms before admission to the hospital was 3.5 days, and 17 patients (81%) were admitted to the ICU less than 24 hours after admission. Mechanical ventilation was initiated in 15 patients, all of whom had ARDS.
As of March 17, mortality was 67%, 24% remained critically ill, and 9.5% had been discharged from the ICU.
The findings emphasize the need to limit exposure of nursing home residents to SAFS-CoV-2, the authors say.Read More >>