April 29, 2021

CDC: Effectiveness of Pfizer-BioNTech, Moderna vaccines in preventing COVID-19-related hospitalizations

By: Judy Mathias
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Editor's Note

In this study, researchers from the Centers for Disease Control and Prevention (CDC) found that COVID-19 vaccines developed by Pfizer-BioNTech and Moderna were 94% effective in preventing hospitalizations in US adults aged 65 and older who were fully vaccinated. The vaccines were 64% effective at preventing hospitalization in those who had received one dose.

The researchers analyzed data on 417 adults aged 65 and older with COVID-19-like symptoms who were admitted to 24 hospitals in 14 states between January 1 and March 26, 2021. Of those patients, 187 tested positive for COVID-19, and 230 tested negative.


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Most (168) patients who tested positive were unvaccinated, 18 had received at least one vaccine dose, and just 1 was fully vaccinated.

A total of 44 patients who tested negative were partially vaccinated, and 18 were fully vaccinated.

The findings suggest that COVID-19 vaccines can reduce the risk for hospitalization, and, as a consequence of preventing severe COVID-19, vaccinations may have an impact on post-COVID-19 conditions, the researchers say.

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