June 12, 2019

Association of TAVR for bicuspid vs tricuspid aortic stenosis with mortality, stroke

By: Judy Mathias
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Editor’s Note

In this study, patients who had transcatheter aortic valve replacement (TAVR) for bicuspid compared with tricuspid aortic stenosis had no significant difference in mortality, but they had a 30-day increased risk of stroke.

In this cohort of 2,691 matched pairs of patients having TAVR for bicuspid vs tricuspid aortic stenosis, there was no significant difference in 30-day (2.6% vs 2.5%) or 1-year (10.5% vs 12.0%) mortality. However, the 30-day risk of stroke was significantly higher for those with bicuspid aortic stenosis (2.5% vs 1.6%).

The researchers concluded that randomized trials will be needed to adequately assess the efficacy and safety of TAVR for bicuspid aortic stenosis.

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